postcholecystectomy diarrhea
Conditions
Interventions
Experimental group:Take Life Enhancer probiotics capsules orally,Twice a day, One at a time
Control Group:Placebo
Sponsors
Shanghai Fourth People's Hospital Affiliated to Tongji University
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: (1) voluntary participation in the study, willing to sign the informed consent; (2) age 18 to 75 years old, gender is not limited; (3) previous cholecystectomy was performed in our hospital because of benign gallbladder disease without other surgery-related complications; The patients had no diarrhea before operation, and had recurrent diarrhea after operation, and the course of disease was =1 month; (4) no other intestinal microflora preparations were taken within 3 months of study entry.
Exclusion criteria
Exclusion criteria: (1) the patients who did not have benign disease of gallbladder only underwent cholecystectomy, such as liver cancer and cholecystectomy at the same time; (2) they had the history of gastrointestinal tract and pancreas operation; (3) colonoscopy can clearly detect organic lesions of the digestive system, such as ulcerative colitis, Crohn's disease and tumors of the digestive system; The patients were diagnosed as functional diseases of the digestive system, such as functional dyspepsia and irritable bowel syndrome (IBS) ; (4)with diarrhea before cholecystectomy or less than one month after cholecystectomy (5) having a severe primary disease or other life-threatening illness; (6) being allergic to a compound probiotic; (7) being pregnant, lactating or not ruling out pregnancy; (8) having participated in other drug trials within 3 months; (9) there are long-term use of yoghurt and other products habitually; (10) researchers do not think that participants.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Remission rate of diarrhea symptoms; | — |
Secondary
| Measure | Time frame |
|---|---|
| Remission rate of other concomitant symptoms of diarrhea;The change of Spectrum of intestinal flora; | — |
Countries
China
Contacts
Public ContactZhenshun Song
Shanghai Fourth People's Hospital Affiliated to Tongji University
Outcome results
None listed