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Prospective and randomized controlled study on the clinical effect of gasless transoral approach and traditional open approach in lateral cervical lymph node dissection of thyroid cancer

Prospective and randomized controlled study on the clinical effect of gasless transoral approach and traditional open approach in lateral cervical lymph node dissection of thyroid cancer

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400082613
Enrollment
Unknown
Registered
2024-04-01
Start date
2024-04-01
Completion date
Unknown
Last updated
2024-04-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Thyroid Cancer

Interventions

Sponsors

Anhui provincial cancer hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: (1) Beauty demand. (2) Differentiated thyroid carcinoma, tumor diameter =2 cm, with cervical lymph node metastasis, but not with distant metastasis.

Exclusion criteria

Exclusion criteria: (1) Limited operation or increased risk of infection due to oral conditions (oral deformity, oral local infection, etc.). (2) Medullary carcinoma and undifferentiated thyroid carcinoma. (3) Severe thyroid inflammatory disease. 5) The tumor is near the entrance of recurrent laryngeal nerve or the larger tumor is located at the upper pole. (6) Previous history of neck surgery, ablation treatment or neck radiation. (7) Patients with complications of other organs or systems who cannot tolerate surgical trauma or general anesthesia. (7) The lymph nodes in the second region of the neck are definitely involved, or the lymph nodes in the second region of the neck are enlarged by more than 3cm. (8) Identify the involvement of lateral cervical nerves and blood vessels.

Design outcomes

Primary

MeasureTime frame
Operation time;Surgical bleeding volume;Surgical complications;Beauty effect evaluation;Number of lymph nodes cleared;

Secondary

MeasureTime frame
C- reactive protein (CRP);Pain score;Postoperative drainage;Days of hospitalization;Follow-up for half a year to evaluate whether the tumor recurs and metastasizes;

Countries

China

Contacts

Public ContactFang Jing

Anhui provincial cancer hospital

fangjing1645@sina.com+86 132 0556 0416

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026