Monogenic diabetes
Conditions
Interventions
Monogenic diabetics:No interventions
Sponsors
People’s Hospital of Xinjiang Uygur Autonomous Region
Eligibility
Sex/Gender
All
Age
No minimum to 45 Years
Inclusion criteria
Inclusion criteria: ? Diagnosis of diabetes mellitus is at age =45 years; ? Family history of diabetes mellitus; ? Atypical type 1 or type 2 diabetes mellitus; ? Progressive decompensation of pancreatic ß-cell secretion during the course of the disease and the need for insulin treatment due to failure of oral medication; ? Progressive hearing loss or deafness; Combination of any of the following: short stature, retinal degeneration, optic nerve atrophy, hyperlipidemia, dilated cardiomyopathy and uremic dysplasia, abnormal nervous system function, hypotonia, slow growth, peculiar facial features, gonadal hypoplasia, and mental retardation. Those who meet ? or ? above, with or without other items, will be screened.
Exclusion criteria
Exclusion criteria: ?Secondary diabetes mellitus;Patients with other endocrine diseases, such as hyperthyroidism or hypothyroidism, hyperparathyroidism or hypothyroidism, acromegaly, Cushing's syndrome, autoimmune multiple endocrine diseases, etc; ?Systemic use of glucocorticoids, immunosuppressants, or other drugs within the past 6 months; ? Patients with malignant tumors.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Types of monogenic diabetes mellitus; | — |
Secondary
| Measure | Time frame |
|---|---|
| Diabetes autoantibody;HbA1c;C-peptide;glucose tolerance; | — |
Countries
China
Contacts
Public ContactYanying Guo
People’s Hospital of Xinjiang Uygur Autonomous Region
Outcome results
None listed