coronary microcirculation disorder
Conditions
Interventions
Gold Standard:Coronary angiography-derived index of microcirculation resistance(caIMR). Using the AngioFlash system(Rainmed), pressure and coronary artery images are imported, and the caIMR is measur
Index test:Nailfold microcirculation. Qualitative and semi-quantitative evaluation of nailfold microcirculation status through nailfold microcirculation microscopy.
Sponsors
Peking University First Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 100 Years
Inclusion criteria
Inclusion criteria: Patients who have been continuously selected for coronary angiography in our department of cardiology due to chest pain and have no significant coronary artery stenosis (=30%). The specific inclusion and exclusion criteria are as follows: ? Age = 18 years old, male or female; ? Patients who have undergone coronary angiography for chest pain and have not been found to have =30% stenosis; ? The coronary angiography image quality is clear and the image meets the caIMR measurement requirements; ? Agree to participate in the study and sign a written informed consent
Exclusion criteria
Exclusion criteria: ? Previous myocardial infarction, coronary intervention therapy or CABG history; ? The target vessel is severely twisted and overlapped; ? Poor image quality, unable to identify the outline of the blood vessels; ? Autoimmune diseases, tumors, severe renal insufficiency (eGFR < 30ml/min/1.73m^2), severe cardiac insufficiency, severe infections, or other diseases that significantly affect the microcirculation status of the nailfold.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| caIMR;microcirculation of nailfold;Accuracy;Sensitivity;specificity; | — |
Countries
China
Contacts
Public ContactTieci Yi
Peking University First Hospital
Outcome results
None listed