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A prospective, randomized controlled study on the clinical effect of gasless transoral approach and traditional open approach in the treatment of thyroid cancer

A prospective, randomized controlled study on the clinical effect of gasless transoral approach and traditional open approach in the treatment of thyroid cancer

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400082540
Enrollment
Unknown
Registered
2024-04-01
Start date
2024-04-01
Completion date
Unknown
Last updated
2024-04-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Thyroid Cancer

Interventions

Sponsors

Anhui provincial cancer hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: (1) Beauty demand. (2) Bilateral differentiated thyroid carcinoma, with a tumor diameter of =2 cm, and no cervical lymph node metastasis or distant organ metastasis, no imaging indication of lymph node metastasis in the central area or metastatic lymph nodes with a diameter of =2 cm without fusion and fixation.

Exclusion criteria

Exclusion criteria: (1) Limited operation or increased risk of infection due to oral conditions (oral deformity, oral local infection, etc.). (2) Medullary carcinoma and undifferentiated thyroid carcinoma. (3) Severe thyroid inflammatory disease. 5) The tumor is near the entrance of recurrent laryngeal nerve or the larger tumor is located at the upper pole. (6) Previous history of neck surgery, ablation treatment or neck radiation. (7) Patients with complications of other organs or systems who cannot tolerate surgical trauma or general anesthesia.

Design outcomes

Primary

MeasureTime frame
Operation time;Surgical bleeding volume;Surgical complications;Evaluate the beauty effect;

Secondary

MeasureTime frame
C- reactive protein (CRP);Pain score;Postoperative drainage;Days of hospitalization;Number of lymph nodes cleared;Follow-up for half a year to evaluate whether the tumor recurs and metastasizes;

Countries

China

Contacts

Public ContactWang Shengying

Anhui provincial cancer hospital

wangshengying61@163.com+86 189 6379 0387

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026