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Effect of ropivacaine combined with dexmedetomidine in quadrat block on postoperative analgesia of gynecological laparoscopic surgery

Effect of ropivacaine combined with dexmedetomidine in quadrat block on postoperative analgesia of gynecological laparoscopic surgery

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400082539
Enrollment
Unknown
Registered
2024-04-01
Start date
2024-04-01
Completion date
Unknown
Last updated
2024-04-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Uterine fibroids, uterine adenomyosis, uterine prolapse, ovarian cysts, adnexal masses, endometrial atypical hyperplasia, uterine intraepithelial neoplasia

Interventions

Experimental group:0.375% Ropivacaine 20ml+ Dexmedetomidine 0.5ug /kg
Control group:0.375% Ropivacaine 20ml

Sponsors

Beijing Miyun District Hospital
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: ASA I ~ II class; Age: 18 ~ 65 years old; Gynecological laparoscopic surgery (including unilateral laparoscopic adnexectomy, unilateral ovarian cyst removal, total hysterectomy, hysteromyomectomy, etc.) is planned to be performed under general anesthesia.

Exclusion criteria

Exclusion criteria: Contraindications to drug use (asthma, hepatorenal insufficiency, digestive tract ulcer, sinus bradycardia, etc.) were involved. Morbid obese patients (BMI> 40kg/m2); Patients who used opioids before surgery; Patients with contraindications of lumboquadrate block (block site infection, etc.); Drug addicts; Patients with alcoholism; Vertigo patients; Patients with chronic constipation; Patients with esophageal reflux; Patients with chronic pain; Intellectual disabilities are unable to complete pain scoring or use patient-controlled intravenous analgesia regimens.

Design outcomes

Primary

MeasureTime frame
Total dose of postoperative relief analgesics;

Secondary

MeasureTime frame
The first postoperative analgesia is required ;Postoperative pain intensity at different time points (including resting and exercise NRS score) ;

Countries

China

Contacts

Public ContactMengyao Qi

Beijing Miyun District Hospital

411420805@qq.com+86 159 1025 9471

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Mar 19, 2026