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Effect of Different Moxibustion Prescriptions and Medicinal Cake Separation Moxibustion on the Treatment of Spleen Kidney Yang Deficiency Type Diarrhea Irritable Bowel Syndrome and Its Influence on Intestinal Microbial Community

Effect of Different Moxibustion Prescriptions and Medicinal Cake Separation Moxibustion on the Treatment of Spleen Kidney Yang Deficiency Type Diarrhea Irritable Bowel Syndrome and Its Influence on Intestinal Microbial Community

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400082525
Enrollment
Unknown
Registered
2024-03-31
Start date
2024-04-01
Completion date
Unknown
Last updated
2024-04-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Diarrhea-predominant irritable bowel syndrome

Interventions

Qumeibutin treatment group:Oral administration of trimebutine
Treatment group of Jianpi Yiqi separated medicinal cake moxibustion:Treatment of Spleen Strengthening and Qi Benefiting with Medicinal Cake Separation Moxibustion
Warm tonifying spleen and kidney separated medicinal cake moxibustion group:Treatment of Warm Tonifying Spleen and Kidney Separating Medicine Cake Moxibustion

Sponsors

Jiaxing First Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1) Western medicine diagnosis conforms to IBS-D, while traditional Chinese medicine syndrome types conform to spleen and kidney yang deficiency syndrome of "diarrhea" or "abdominal pain"; 2) Age range from 18 to 60 years old; 3) Voluntarily accept treatment and sign an informed consent form. Only patients who meet the above three criteria can be included in this study.

Exclusion criteria

Exclusion criteria: 1) Pregnant or lactating women; 2) Diarrhea is caused by other reasons, including gastrointestinal ulcers, viral and bacterial infections, etc; 3) Other subtypes of IBS - Constipation type, mixed type, and amorphous type, as well as other traditional Chinese medicine syndrome types; 4) Merge gastrointestinal masses, obstruction, perforation, etc; 5) Take traditional Chinese medicine, traditional Chinese patent medicines and simple preparations, anti-inflammatory drugs and other drugs that may affect visceral sensitivity in the past 2 months; 6) Individuals who are allergic to traditional Chinese medicine powder or moxibustion used in this study; 7) Patients who are participating in clinical studies of other drugs.

Design outcomes

Primary

MeasureTime frame
efficacy index;Laboratory testing (observing and recording the proportion of fecal bacteria in fecal smears, and testing the number of intestinal bifidobacteria and Escherichia coli in fecal culture);

Secondary

MeasureTime frame
Traditional Chinese Medicine Clinical Symptom Scoring;IBS-SSS Total Integral;Recurrence rate;

Countries

China

Contacts

Public ContactZhang Aijun

Jiaxing First Hospital

zhangaijun77@126.com+86 139 6736 3972

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026