Myocardial Infarction Reperfusion Injury
Conditions
Interventions
Treatment group:Conventional clinical western medicine treatment + transcutaneous acupoint electrical stimulation of the ST36(Zu SanLi)/PC6 ( Nei Guan ) treatment, using transcutaneous electrical stim
Control group:Conventional clinical western medicine treatment + transcutaneous acupoint electrical stimulation of the ST36(Zu SanLi)/PC6 ( Nei Guan ) treatment, using transcutaneous electrical stimul
Sponsors
The Third Affiliated Clinical Hospital of Changchun University of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Meet the diagnostic criteria for acute ST-segment elevation myocardial infarction in the 2017 edition of the European Society of Cardiology Guidelines; 2. Patients receiving emergency PCI treatment for the first time with acute chest pain symptoms<12 hours; 3. Gender unlimited, age = 18 years old,<80 years old, subject to informed consent; 4. Abnormal elevation of myocardial injury markers;
Exclusion criteria
Exclusion criteria: 1.Previous history of myocardial infarction, coronary stent implantation, or coronary artery bypass grafting; 2. patients with severe heart failure, ECG showing right and left ventricular hypertrophy, intraventricular differential conduction, pre-excitation syndrome, and extreme cis-clockwise transposition, ventricular fibrillation, and post-cardiopulmonary resuscitation; 3. Killip cardiac function = grade 4; 4. patients with malignant tumors, severe infectious diseases, inflammatory diseases, autoimmune diseases, hematologic diseases, and acute cerebral infarction; 5. Participation in any other drug study or therapeutic study using an unapproved drug within the previous 3 months. Note: Patients who meet any 1 of the above criteria are excluded.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Infarct Size; | — |
Secondary
| Measure | Time frame |
|---|---|
| Left ventricular ejection fraction;NT-proBNP;IL-6;IL-1ß;TNF-a;Major adverse cardiovascular events;CK-MB;MYO; | — |
Countries
China
Contacts
Public ContactHongfeng Wang
The Third Affiliated Clinical Hospital of Changchun University of Traditional Chinese Medicine
Outcome results
None listed