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A single-center randomized controlled clinical study on the safety and effectiveness of temporal asynchronous visual stimulation in the treatment of amblyopia in adults

A single-center randomized controlled clinical study on the safety and effectiveness of temporal asynchronous visual stimulation in the treatment of amblyopia in adults

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400082505
Enrollment
Unknown
Registered
2024-03-30
Start date
2024-04-05
Completion date
Unknown
Last updated
2024-04-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Adult amblyopia

Interventions

The experimental group:Temporal asynchronous binocular visual stimulation, by allowing the non-dominant eye to perceive the visual image first, and the dominant eye to receive the visual image later,
The control group:Temporally symmetrical binocular visual stimulation by allowing both eyes to receive visual images at the same time

Sponsors

China Rehabilitation Research Center
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: (1) Age 18 and above, regardless of gender; (2) Diagnosed as amblyopia patient through outpatient examination; (3) The difference in refractive power between binocular hyperopia spherical lenses is greater than 1.50 DS, or the difference in refractive power between cylindrical lenses is greater than 1.00 DC; (4) 0.2 logMAR difference in binocular vision; (5) Having undergone optical correction glasses for corrected vision for at least two months; (6) No organic lesions were found in both eyes during clinical examination; (7) Has not received any training on simple occlusion or other amblyopia within the past month;

Exclusion criteria

Exclusion criteria: (1) Clinical examination reveals organic lesions; (2) Participants have received simple occlusion or other amblyopia training within the past month; (3) Participants have any acute or chronic diseases or hereditary visual system diseases; (4) Participants have a history of strabismus; (5) Known to be allergic to dilated pupil drugs such as atropine; (6) Individuals with a known history of eye surgery; (7) Other situations where researchers consider it inappropriate to participate in clinical trials.

Design outcomes

Primary

MeasureTime frame
vision;contrast sensitivity;

Secondary

MeasureTime frame
stereopsis;

Countries

China

Contacts

Public ContactZHOU JIE

China Rehabilitation Research Center

ashily.hi@163.com+86 136 0137 2859

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026