metabolic syndrome and related component diseases
Conditions
Interventions
NA:NA
Sponsors
West China hospital of Sichuan university
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Patients =18 years of age with MetS and related component diseases (meeting any of the following diagnostic criteria) who were treated at a medical institution: (1) Overweight or central obesity: BMI=22.5 kg/m2, or waist circumference =90cm for men and =85cm for women, or waist-height ratio > 0.5 (2) Diabetes or pre-diabetes: fasting blood glucose =5.6 mmol/L or 2 hours after meals blood glucose > 7.8 mmol/L or HbA1c > 5.7% or diagnosed diabetes (including not used or under treatment with hypoglycemic drugs) (3) Hypertension: systolic blood pressure =130 mmHg or diastolic blood pressure =85 mmHg or being treated with antihypertensive drugs (4) Dyslipidemia: serum TG=150 mg/dL (1.7 mmol/L) or serum HDL-c < 40mg/dL (1.03mmol/L) for men and less than 50mg/dL (1.29mmol/L) for women, or under the treatment of hypolipidemic drugs (5) MAFLD: Liver fat accumulation or fatty liver, as determined by histology or imaging, combined with at least one of the above four conditions (6) Hyperuricemia: In the case of normal purine diet, fasting blood uric acid level exceeds 420µmol/L twice on different days or is receiving drug treatment for hyperuricemia For the retrospective study, the included patients had been followed up at the participating medical institutions for =3 years For prospective studies, included patients were willing to sign the study informed consent
Exclusion criteria
Exclusion criteria: 1 With severe mental illness, end-stage cancer or communication, cognitive dysfunction and other serious health problems. 2. Medical records that are missing or incomplete to the extent that they cannot effectively verify their diagnosis and treatment history will be excluded. 3. Any other circumstances deemed unsuitable for inclusion by the investigator.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Body weight;blood glucose;blood pressure;blood lipids; | — |
Secondary
| Measure | Time frame |
|---|---|
| liver fat;blood uric acid; | — |
Countries
China
Contacts
Public ContactNanwei Tong
West China hospital of Sichuan university
Outcome results
None listed