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Comparison of Ultrasound-guided Near the Intercostal Space Block and Thoracic Paravertebral Block for Postoperative Analgesia in Thoracoscopic Radical Lung Cancer Surgery

Comparison of Ultrasound-guided Near the Intercostal Space Block and Thoracic Paravertebral Block for Postoperative Analgesia in Thoracoscopic Radical Lung Cancer Surgery: A prospective, randomized, controlled study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400082500
Enrollment
Unknown
Registered
2024-03-29
Start date
2024-03-29
Completion date
Unknown
Last updated
2024-04-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Complications of partial pneumonectomy

Interventions

BP:Paravertebral block was performed with methylene blue before surgery
MN:Near intercostal block was used after operation
UP:Paravertebral block was used after operation
UN:Near intercostal block was used after operation
MP:Paravertebral block was used after operation
BN:Near intercostal block was performed with methylene blue before surgery

Sponsors

Union Hospital affiliated to Fujian Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: (1) All voluntarily signed an informed consent form before the start of anesthesia; (2) They are older than 18 years old, have an American Society of Anesthesiologists (ASA) classification of I-III, and have a body mass index (BMI) of less than 40 kg/m2 ; (3) Patients who were to undergo elective unilateral thoracoscopic partial lung resection and were first-time patients undergoing thoracoscopic radical lung cancer surgery (patients whose surgery ended before 11:00 a.m.); (4) Patients with the ability to determine pain scores.

Exclusion criteria

Exclusion criteria: (1) Psychiatric systemic illness or poor compliance to complete the experiment; (2) Acute lung infection in the last 4 weeks; (3) History of intrathoracic surgery, pneumothorax, branchial dilatation, tuberculosis, and fibrosis; (4) Patients with allergy or known history of allergy to the drugs specified in the study protocol of this project (drugs such as ropivacaine, propofol, sufentanil, rocuronium bromide, remifentanil, etc.) and their excipients; (5) Preoperative use of hormonal drugs (within 6 months); (6) Combined autoimmune disease, connective tissue disease, etc. requiring long-term treatment with adrenocorticotropic hormone; (7) Those who are addicted and resistant to opioids; (8) Intraoperative/postoperative fatal complications such as hemorrhage and anaphylactic shock; (9) Those with intermediate open-heart surgery; (10) Patients with a history of chronic pain or long-term use of opioid analgesics, general anesthetics, sedatives, hypnotics or other central nervous system depressants; (11) Patients with severe cardiac, hepatic or renal insufficiency; (12) Coagulation dysfunction.

Design outcomes

Primary

MeasureTime frame
Postoperative pain score;Total postoperative sufentanil dosage;Time of pain relief pump for the first time after surgery;

Secondary

MeasureTime frame
Methylene blue diffusion gap;Percentage of area in the methylene blue spine area;The rate of methylene blue metabolism;Inflammatory index;stress index;Mean arterial pressure;Postoperative pain in the interscapular region;Incidence of postoperative nausea and vomiting;Use of postoperative remedial analgesics;

Countries

China

Contacts

Public ContactZhongmeng Lai

Fujian medical university union hospital

angerer1980@163.c0m+86 133 9500 0771

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: May 23, 2026