Salt-sensitive hypertension
Conditions
Interventions
Trail group:None
Sponsors
The First Affiliated Hospital of Chengdu Medical College
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: (1) 18 to 65 years old, gender is not limited; (2) Patients who were clearly diagnosed with primary hypertension, with reference to the Chinese Guidelines for the Prevention and Treatment of Hypertension (2018 Revision) for the basis of diagnostic criteria; (3) Patients who met the diagnostic criteria for salt-sensitive hypertension, with reference to the Chinese Expert Consensus on the Management of Salt-Sensitive Hypertension (2023) for the basis of diagnostic criteria; (4) Voluntary participation; (5) Complete clinical data and laboratory tests; (6) Written informed consent approved by the ethics committee should be signed by the patients or their legal representatives before screening.
Exclusion criteria
Exclusion criteria: (1) Patients with secondary hypertension; (2) Women who have been pregnant or breastfeeding; (3) Patients with severe organic diseases, especially hepatic and renal dysfunction; (4) Acute heart failure, cardiogenic shock, acute coronary syndrome and previous myocardial infarction; (5) Acute stage of stroke (<3 months); (6) Patients with other severe organic diseases with a life expectancy of <12 months; (7) Illiteracy, impaired basic reading and writing functions, or inability to care for oneself; (8) Left ventricular ejection fraction < 50%; (9) Patients who were unsuitable for the study for any reason according to the judgment of the investigator.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Carotid intima-media thickness;Left ventricular hypertrophy;Estimated glomerular filtration rate;Urine microalbumin; | — |
Secondary
| Measure | Time frame |
|---|---|
| Pulse wave velocity;Ankle brachial pressure index;Cranial imaging; | — |
Countries
China
Contacts
Public ContactWang Peijian
The First Affiliated Hospital of Chengdu Medical College
Outcome results
None listed