Effect and mechanism of oral curcumin capsule on delirium in elderly patients after radical resection of gastrointestinal tumors

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2400082484

Enrollment

Unknown

Registered

2024-03-29

Start date

2024-04-01

Completion date

Unknown

Last updated

2024-04-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

POD

Interventions

1:500mg

2:0

Eligibility

Sex/Gender

All

Age

60 Years to 80 Years

Inclusion criteria

Inclusion criteria: Age 60-80 years old; ASA grade ? ~?; BMI=28kg/m²; Laparoscopic radical resection of gastrointestinal tumors under general anesthesia (operation time 2-6 hours); Sign the informed consent form.

Exclusion criteria

Exclusion criteria: Patients who are unable to take oral medication (e.g. gastrointestinal obstruction); Severe hypertension or diabetes; Heparin resistance; A history of alcoholism; Inability to communicate before surgery (coma, deep dementia or speech problems, severe visual and hearing impairments); Preoperative mini-mental state examination (MMSE) score was too low [illiteracy < 17, primary school < 20, secondary school (including technical secondary school) < 24]; Severe heart, liver and kidney disease; History of neurological or psychiatric disorders.

Design outcomes

Primary

Measure	Time frame
POD;	—

Secondary

Measure	Time frame
IL-1ß;IL-6;TNF-a;CRP;MCP-1;	—

Countries

China

Contacts

Public ContactGong Gu

The General Hospital of Western Theater Command

gonggu@163.com+86 173 6013 7572

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026