Carbapenem-resistant gram-negative bacterial infections
Conditions
Interventions
Case series:None
Sponsors
Zhejiang Provincial People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: 1) =18 years old; 2) Patients with clinically and microbiologically confirmed CRE or CRPA infections; 3) Patients receiving intravenous Ceftazidime-Avibactam therapy; 4) Willing to participate in this study and sign the informed consent form; if the subject lacks the ability to understand or sign the informed consent form, their legal guardian will act on their behalf in the informed consent process and agree to their participation in this study.
Exclusion criteria
Exclusion criteria: 1) Patients with positive cultures for CRE or CRPA without evidence of infection (colonized patients); 2) Patients infected with CRE or CRPA resistant to Ceftazidime-Avibactam; 3) Pregnant or lactating women; 4) Patients with a Ceftazidime-Avibactam treatment duration of less than 3 days or who are allergic.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Ceftazidime-Avibactam concentration; | — |
Countries
China
Contacts
Public ContactYunsong Yu
Zhejiang Provincial People’s Hospital
Outcome results
None listed