Liver transplant
Conditions
Interventions
wild type group:Non-intervention
Mutant type group:Non-intervention
Sponsors
Zhong Shan Hospital, Fudan University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1: Han Chinese 2: First time for liver transplantation 3: The primary disease is hepatocellular carcinoma 4: Age 18-65 5: Weight > 40kg, height > 150cm 6: Accepting single or combination immunosuppressive therapy based on sirolimus (rapamycin, Wyeth Pharmaceuticals) 7: Complete follow-up data available 8: Being able to fully understand the purpose of this study and potential adverse reactions, voluntarily participating in the experiment and signing an informed consent form
Exclusion criteria
Exclusion criteria: 1: patients who do not accept the standard dosing regimen 2: Non first-time transplant or combined organ transplant patients 3: Time of SRL using <1 year 4: Patients with active gastrointestinal ulcers, malabsorption syndrome, or gastrointestinal resection surgery which affects drug absorption
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Rejection; | — |
Secondary
| Measure | Time frame |
|---|---|
| Recurrence rate of hepatocellular carcinoma;survival rate of graft;renal function;liver function;Blood lipid level;Blood cell level; | — |
Countries
China
Contacts
Public ContactXu Qinxia
Zhong Shan Hospital, Fudan University
Outcome results
None listed