kidney transplantation
Conditions
Interventions
Sponsors
Sichuan Provincial People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: ? Recipient of the first kidney transplant ? Age = 18 years old ? Immunosuppressive therapy plan: Tacrolimus capsules (Sifukai® or Prograf®) + Mycophenolic acid drugs + Hormone triple immunosuppressive therapy plan
Exclusion criteria
Exclusion criteria: ? ABO incompatible transplantation ? Multi-organ transplantation ? Recipient of bilateral kidney transplantation ? Recipient of second or multiple kidney transplantation ? Subjects with severe and uncontrolled systemic infection and/or severe diarrhea, vomiting, active upper gastrointestinal disease that may affect tacrolimus absorption, or active peptic ulcer ? Recipients or donors known to be positive for HIV, HCV, or HBV ? Subjects receiving immunosuppressive drugs for any other indication besides transplantation ? Other cases deemed inappropriate for inclusion by the investigator due to missing key information or other reasons ? Patients who switched tacrolimus manufacturers during the current hospitalization period after kidney transplantation ? Subjects who failed to respond to three consecutive follow-up visits
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Survival rate of transplant recipients at 24 months postoperatively;The survival rate of the transplanted organ at 24 months postoperatively; | — |
Secondary
| Measure | Time frame |
|---|---|
| Patient survival rate at 3, 6, and 12 months postoperatively;Graft survival rates at 3, 6, and 12 months postoperatively;Incidence rate of acute rejection reactions;Graft survival rate without acute rejection reactions at 24 months postoperatively;Cumulative incidence of chronic kidney allograft injury at 12 and 24 months postoperatively;Cumulative incidence of transplantation failure at 3, 6, 12, and 24 months postoperatively;Changes in renal function (blood creatinine, glomerular filtration rate, cystatin C) at 3, 6, 12, and 24 months postoperatively;Incidence rate of delayed graft function (DGF); | — |
Countries
China
Contacts
Public ContactYang Hongji
Sichuan Provincial People's Hospital
Outcome results
None listed