Cognitive impairment
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: The diagnosis of cerebral infarction met the diagnostic criteria of the Chinese Guidelines for the Diagnosis and Treatment of Acute Ischemic Stroke 2018. (1) Cognitive dysfunction: Moca scale score below 21 points; (2) Consistent with the clinical manifestations of cognitive dysfunction, imaging examinations, neuropsychological scales, etc.; (3) Imaging lesions, course of disease: within 18 months; (5) Age: 18-80 years old; (6) The results of non-invasive cardiac output measurement/pulmonary ventilation function measurement/cardiopulmonary exercise test were determined by stable basic disease control, stable vital signs, and able to cooperate with treatment. (7) Patients and their families voluntarily cooperate and sign an informed consent form.
Exclusion criteria
Exclusion criteria: (1) Vital signs are unstable; (2) Cerebral hemorrhage; (3) Combined with dissecting aneurysm, moderate to severe aortic regurgitation, significant pulmonary hypertension, active phlebitis, venous thrombosis, pregnancy, and arterial occlusive disease of the lower limbs. (4) Severe circulatory system, respiratory system, locomotor system and other diseases, such as severe atrial fibrillation, heart failure, lung infection, severe liver and kidney insufficiency and other serious disease states; (5) Combined with other diseases of the nervous system; (6) Skin ulceration and infection of both lower limbs caused by other reasons, such as fractures of both lower limbs, diabetes, etc.; (7) Unable to cooperate with the completion of examinations, such as mental disorders, severe vision and hearing abnormalities, etc.; (8) Patients with abnormal coagulation function; (9) Other reasons: refusal to participate.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Cardiac output;EEG signals;Montreal Cognitive Assessment and Mini-mental State Examiniation and Developmental Screen Test; | — |
Countries
China
Contacts
Nanyang Central Hospital