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Application of autologous vascularized soft and bone tissue flap in mandibular reconstruction of patients with advanced oral cancer

Application of autologous vascularized soft and bone tissue flap in mandibular reconstruction of patients with advanced oral cancer

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2400082445
Enrollment
Unknown
Registered
2024-03-29
Start date
2024-04-01
Completion date
Unknown
Last updated
2024-04-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Oral cancer

Interventions

Autologous vascularized soft tissue flap:None
Autologous vascularized bone tissue flap:None

Sponsors

Hospital of Stomatology, Wuhan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: From 2016 to 2023, patients with advanced oral cancer underwent mandibular segmental resection in the Department of Head and Neck Oncology, Stomatology Hospital of Wuhan University, and received supplementary chemoradiotherapy in the Department of Head and Neck Oncology, Zhongnan Hospital of Wuhan University.

Exclusion criteria

Exclusion criteria: (1) Patients with advanced oral cancer did not involve the jaw; (2) Patients with advanced oral cancer did not receive postoerative supplemental chemoradiotherapy; (3) Patients who did not receive late treatment in Zhongnan Hospital of Wuhan University.

Design outcomes

Primary

MeasureTime frame
Flap survival;Quality of life;Radiation osteonecrosis;Survival;Sub-water test ;Mouth opening;—

Secondary

MeasureTime frame
Defect type;TNM stage;—

Countries

China

Contacts

Public ContactBing Liu

Hospital of Stomatology, Wuhan University

liubing9909@whu.edu.cn+86 138 7111 6858

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026