Stress response to tracheal intubation
Conditions
Interventions
Control Group:TCL Sufentanil
TEAS Group:TCL Sufentanil + Continuous electrical stimulation of Neiguan and Hegu points for 30 minutes before induction
Sham Group:TCL Sufentanil + Only attach electrode pads
Sponsors
Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Chinese Traditional Medicine
Eligibility
Sex/Gender
All
Age
65 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Patients scheduled for VATS lung surgery with VDLT intubation and general anesthesia; 2. Frail patients (FRAIL scale =3 points); 3. The patient’s age is =65 years old and =75 years old; 4. Those who sign the informed consent form; 5. Relevant auxiliary examinations have been completed, such as blood routine, lung function, liver and kidney function, bleeding and coagulation function, etc.
Exclusion criteria
Exclusion criteria: 1. There are drug abusers; 2. The surgical plan is temporarily changed to thoracotomy or bilateral surgery; 3. Patients who are allergic to amide local anesthetics or DET or DEM; 4. Preoperative basal heart rate is lower than 50bpm; 5. Patients with cognitive dysfunction, language impairment, and poor ability to understand scales; 6. Patients with confirmed mental illness; 7. Patients who have had a history of acupuncture treatment; 8. Patients with New York Heart Association (NYHA) cardiac function class III-IV; 9. Patients with Canadian Cardiovascular Society (CCS) coronary heart disease classification III-IV; 10. Patients with end-stage liver disease or end-stage renal disease (glomerular filtration rate GFR <15ml/min)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Sufentanil EC95; | — |
Secondary
| Measure | Time frame |
|---|---|
| Sufentanil EC50;blood pressure;heart rate;bispectral index;catecholamine;steroid;Airway score;Sufentanil dosage;Propofol dosage;postoperative nausea and vomiting;throat irritation;rescue analgesic medication and dosage for the last 24 hours;First time out of bed activity time and amount of exercise;saturation of pulse oximetry; | — |
Countries
China
Contacts
Public ContactXu Hua
Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Chinese Traditional Medicine
Outcome results
None listed