Bacterial vaginosis
Conditions
Interventions
VMT Group:Lactobacillus crispatus
Placebo Group:Placebo
Sponsors
Zhujiang Hospital, Southern Medical University
Eligibility
Sex/Gender
Female
Age
18 Years to 55 Years
Inclusion criteria
Inclusion criteria: 1. History of sexual behaviour; 2.18-55 years old; 3. Women were diagnosed as bacterial vaginosis; 4. Asexual life 3 days before sampling. 5. Voluntarily sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1. During pregnancy, or within 8 weeks after delivery; 2.Use of broad-spectrum antibiotics or local probiotics or vaginal suppositories in the reproductive tract in recent January; 3. presence of systemic diseases (such as SLE, malignant tumors, etc.)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| BV recurrence rate at month 12; | — |
Secondary
| Measure | Time frame |
|---|---|
| BV cure rate at 2 weeks , month 1 ,month 3, month 6,month 12;BV recurrence rate at 2 weeks , month 1 ,month 3, month 6,month 12;Changes of microflora at 2 weeks , month 1 ,month 3, month 6,month 12;Colonization of Lactobacillus at 2 weeks , month 1 ,month 3, month 6,month 12;Clearance of other pathogenic infections at 2 weeks , month 1 ,month 3, month 6,month 12;Inflammatory reaction improves the situation at 2 weeks , month 1 ,month 3, month 6,month 12; | — |
Countries
China
Contacts
Public ContactHongwei Zhou
Zhujiang Hospital of Southern Medical University
Outcome results
None listed