Heart failure
Conditions
Interventions
Treatment group:Standard treatment combination with oral Yiqi Huayu decoction granules orally, two bags a day, twice a day, 200ml of water
control group:Standard treatment combined with oral Yiqi Huayu decoction granule simulator, two bags a day, twice a day, 200ml water
Treatment group:Standard treatment combination with oral qiang xin decoction granules orally, two bags a day, twice a day, 200ml of water
control group:Standard treatment combination with oral qiang xin decoction granules simulator, two bags a day, twice a day, 200ml of water
Treatment group:Standard treatment combination with oral ziyin yangshen decoction granules orally, two bags a day, twice a day, 200ml of water
control group:Standard treatment combination with oral ziyin yangshen decoction granules simulator, two bags a day, twice a day, 200ml of water
Sponsors
Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
40 Years to 80 Years
Inclusion criteria
Inclusion criteria: At the same time, it meets the diagnostic criteria of Western medicine and Chinese medicine for the heart failure with ejection fraction preservation. Age 40 ~ 80 years old; The patient has complete basic information, can adhere to medication, and has follow-up conditions; Patients and their families were aware of the purpose of the study, signed informed consent, and voluntarily participated in the study.
Exclusion criteria
Exclusion criteria: Concomitant with restrictive (invasive) cardiomyopathy and congenital heart disease Acute coronary syndrome History of stent implantation, coronary artery bypass, permanent pacemaker implantation, and implantable defibrillator implantation within the last 90 days (from the time of admission); eGFR=20ml/min/1.73 m2, severe liver insufficiency Complicated with malignant tumor, hematopoietic system disease, acute infectious disease Urine pregnancy positive, breastfeeding or pregnant women Patients suffering from mental illness or infectious diseases
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Re-hospitalization or cardiovascular mortality due to worsening heart failure at 180 days; | — |
Secondary
| Measure | Time frame |
|---|---|
| 180-day all-cause mortality;NT-proBNP;echocardiography;electrocardiogram;Plasma transcriptomics;Metabolomics of plasma;Minnesota Heart Failure Questionnaire score;Kansas City heart muscle scale;TCM syndrome score;Lipid set;6 minutes walking test;H2FPEF score; | — |
Countries
china
Contacts
Public ContactXiaolong Wang
Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine
Outcome results
None listed