Benign airway stenosis
Conditions
Interventions
Experimental group:The patients in the experimental group were given erythromycin ethylsuccinate tablets 0.25g 2/ day orally combined with budesonide suspension 0.5mg 2/ day by aerosol inhalation
Control group:Patients in the control group were not given any drugs after interventional treatment
Sponsors
Tangdu Hospital
Eligibility
Sex/Gender
All
Age
12 Years to 80 Years
Inclusion criteria
Inclusion criteria: (1) The patients were diagnosed as benign traumatic airway stenosis or infectious airway stenosis according to their past medical history, clinical symptoms, chest imaging examination, electronic bronchial examination, TBLB or brushing biopsy of local mucosa. (2) interventional therapy was planned; (3) Informed consent was obtained.
Exclusion criteria
Exclusion criteria: (1) concomitant with other systemic diseases such as connective tissue diseases, systemic lupus erythematosus, etc.; (2) patients with unstable vital signs, severe liver and kidney dysfunction, basic cardiopulmonary function can not tolerate interventional surgery, and allergy to anesthetics; (3) patients who were contraindicated or unsuitable to use erythromycin or budesonide; (4) patients with BMI 80 years old; (5) using other drugs that may affect the study; (6) pregnancy, lactation and mental disorders.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Degree of airway stenosis; | — |
Secondary
| Measure | Time frame |
|---|---|
| Pulmonary Function Tests(FEV1.PEF);Shortness of breath index score;Interval between treatments;Number of interventional procedures; | — |
Countries
China
Contacts
Public ContactJin Faguang
Tangdu Hospital, Air Force Medical University
Outcome results
None listed