Mild Cognitive Impairment
Conditions
Interventions
Time Sequnce Group 1:Tai chi training combined with transcranial direct current stimulation.The participants undergo a 60-minute Tai Chi training session followed by a 20-minute, 2mA anodal transcrani
Time Sequnce Group 2:Tai chi training combined with transcranial direct current stimulation.The participants undergo a 20-minute, 2mA anodal transcranial direct current stimulation (tDCS) session foll
Control Group:Tai chi training combined with transcranial direct current stimulation.The participants undergo a combined intervention of Tai Chi training and transcranial direct current stimulation (t
Sponsors
Rehabilitation Industry Institute of Fujian University of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
50 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Meet the diagnostic criteria of MCI; 2. The score of Montreal Cognitive Assessment scale(MoCA) higher than 18 and lower than 26, and if the years of education were less than 12 years, the score should be added 1 score; 3. The score of Activity of Daily Living Scale(ADL) less than 22; 4. Meet the level of global deteriorate scale 2-3; 5. Aged 50 to 75 years; 6. Not engaged in regular exercise in the last six months (regular exercise means exercise with a frequency of at least three times a week and at least 20 min per session); 7. No contraindications of tDCS; 8. The Participants had informed consent and participated voluntarily.
Exclusion criteria
Exclusion criteria: 1. Patients with cognitive impairment caused by depression,the depression patients with score of GDS-15 more than or equal 9; 2. Patients with cognitive impairment caused by taking drugs (antipsychotics; benzodiazepines, etc.), poisoning and other reasons; 3. Patients with uncontrollable blood pressure (systolic blood pressure greater than 160mmHg or diastolic blood pressure greater than 100 mmHg after medication); 4. Participants cannot cooperate to complete the exercise program, such as motor dysfunction caused by nervous system diseases (stroke, Parkinson's disease), musculoskeletal system diseases (lower limb arthritis, history of hip and knee replacement, etc.), serious organ diseases and other exercise contraindications; 5. Participants cannot complete the index evaluation, such as severe aphasia, audio-visual impairment, illiteracy, etc; 6. Participants in other research trials that are participating in and influencing the results of this study; 7. Taking any medications in the past 6 months which may cause impaired or improved cognitive performance.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Chinese revised version of the Wechsler Adult Memory Scale; | — |
Secondary
| Measure | Time frame |
|---|---|
| Montreal Cognitive Assessment Scale;Auditory word learning test;Rey-Osterrieth complex graphics test;N-Back working memory test;Delay matching sample test;EEG neural rhythms;Cerebral blood oxygen concentration; | — |
Countries
China
Contacts
Public ContactXu Ying
Rehabilitation Industry Institute of Fujian University of Traditional Chinese Medicine
Outcome results
None listed