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Real-World Study of Magnetic Resonance-guided Laser Interstitial Thermal Therapy for Patients with Drug-resistant Epilepsy

Demonstration of minimally invasive treatment of refractory epilepsy with magnetic resonance-guided laser interstitial thermotherapy (LITT) system

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2400082400
Enrollment
Unknown
Registered
2024-03-28
Start date
2024-04-01
Completion date
Unknown
Last updated
2024-04-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

epilepsy

Interventions

LITT surgery:LITT surgical treatment

Sponsors

Beijing TianTan Hospital, Capital Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
2 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1) Age: 2-75 years; 2) The standard preoperative evaluation process was completed and a diagnosis of focal epilepsy was made; 3) Seizures are not relieved by regular, adequate dose and course of 2 or more antiseizure medications; 4) Patients signed an informed consent form.

Exclusion criteria

Exclusion criteria: 1) Presence of severe mental, cognitive, and psychological disorders that prevent them from cooperating with the research as well as follow-up; 2) Failure to clearly localize the epileptogenic zone or inappropriateness of LITT treatment; 3) Other treatment options exist that are more beneficial to the patient; 4) Other conditions that, in the opinion of the researcher, are not appropriate for participation in the research.

Design outcomes

Primary

MeasureTime frame
Seizure-freedom rate;

Secondary

MeasureTime frame
Seizure Frequency;Improvement of seizures;Seizure Severity;Improvement of EEG;Cognitive function outcomes;Memory function outcomes;Total hospitalization days;Total cost;Quality-of-life;Long-term financial burden;

Countries

China

Contacts

Public ContactKai Zhang

Beijing TianTan Hospital, Capital Medical University

zhangkai62035@163.com+86 59978000

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026