Primiparous
Conditions
Interventions
Group A (23G spinal needle):Labor analgesia with DPE technique (Dural puncture with 23G Whitacre needle)
Group A (23G spinal needle):Labor analgesia with DPE technique (Dural puncture with 25G Whitacre needle)
Group C(27G spinal needle):Labor analgesia with DPE technique (Dural puncture with 27G Whitacre needle)
Group D (epidural):Routine epidural labor analgesia
Sponsors
Shaoxing Maternity and Child Health Care Hospital
Eligibility
Sex/Gender
Female
Age
20 Years to 40 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria Singleton, cephalic presentation, primipara; aged 20-40 years, gestational age 37-42 weeks; body mass index (BMI) less than 40; ASA I-II, no obstetric, medical and surgical complications; in line with the diagnostic criteria for labor, vaginal trial of labor intention and obstetric examination after vaginal trial of labor indications; expected fetal weight 2.5-4.0 kg; did not receive any other drugs and/or non-drug analgesia; study subjects voluntarily accepted the study and signed informed consent.
Exclusion criteria
Exclusion criteria: Exclusion criteria: Contraindications to spinal block; termination or change of labor analgesia methods required by parturients or their families during the study; blood samples could not be obtained during the study; severe adverse reactions occurred in parturients during delivery; psychiatric patients; patients or their families proposed to withdraw from the trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| VAS score; | — |
Secondary
| Measure | Time frame |
|---|---|
| onset time of analgesia;Time to reach peak analgesia;Levels of IL-1ß, IL-8, ß-endorphin and cortisol in peripheral blood and neonatal cord blood;Modified Bromage Score;Apgar score at 1 min and 5 min; | — |
Countries
China
Contacts
Public ContactChenjiefeng
Shaoxing Maternity and Child Health Care Hospital
Outcome results
None listed