Chronic atrophic gastritis with intestinal metaplasia
Conditions
Interventions
Experimental group:Wen Wei San Ji Gao, oral, three times a day, one tablespoon each time (15-18 milliliters)
Sponsors
Shaanxi Provincial Traditional Chinese Medicine Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: Only those who possess all of the following items can be included: (1) Patients diagnosed by Western medicine with chronic atrophic gastritis accompanied by intestinal metaplasia; (2) Traditional Chinese medicine syndrome differentiation belongs to those with spleen and stomach weakness and stomach meridian stasis syndrome; (3) Hp negative individuals or those with Hp infection who have undergone eradication treatment and become negative again after one month; (4) Individuals aged between 18 and 75 years old; (5) Those who voluntarily participate in this clinical study and have signed an informed consent form should comply with ethical principles in the process of signing the informed consent form.
Exclusion criteria
Exclusion criteria: Individuals who meet any of the following criteria are not eligible to participate in this experiment: (1) Patients who have undergone previous stomach surgery or require surgery for gastrointestinal diseases; (2) Pregnant or preparing pregnant women (excluding those who require termination of pregnancy), lactating women; (3) Allergic constitution, such as a history of allergies to two or more drugs or foods; Individuals who are known to be allergic to the ingredients of this medicine; (4) Patients who have participated in clinical studies of other drugs within 3 months; (5) According to the researcher's judgment, other patients who are deemed unsuitable to participate in clinical trials, such as other lesions that reduce the likelihood of enrollment or complicate enrollment, such as frequent changes in the work environment, are prone to loss of follow-up;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Changes in total score before and after endoscopic histopathological treatment;Changes in single integral score of gastroscopy histopathology before and after treatment; | — |
Secondary
| Measure | Time frame |
|---|---|
| Pathological efficacy and effectiveness;Single symptom efficacy;Traditional Chinese Medicine Syndrome Therapeutic Effect;Changes in measured values of various indicators of gastrointestinal tumor markers before and after treatment;Changes in measured values of gastrin-17 before and after treatment;Changes in measured values of pepsinogen before and after treatment; | — |
Countries
China
Contacts
Public ContactWen Xinli
Shaanxi Provincial Traditional Chinese Medicine Hospital
Outcome results
None listed