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Effects of Vitamin A on Metabolic Health in Heat-Exposed Populations: A Prospective, Single-Center, Randomized Controlled Trial

Effects of Vitamin A on Metabolic Health in Heat-Exposed Populations: A Prospective, Single-Center, Randomized Controlled Trial

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400082356
Enrollment
Unknown
Registered
2024-03-27
Start date
2024-03-30
Completion date
Unknown
Last updated
2025-11-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Metabolic diseases

Interventions

Experimental group:Vitamin A intervention

Sponsors

The First People's Hospital of Xiangtan City
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 55 Years

Inclusion criteria

Inclusion criteria: 1. Body Mass Index (BMI) between 18.5 and 28 inclusive; 2. Age between 18 and 55 inclusive; 3. In good physical and mental health; 4. The subject and their immediate family members fully understand the informed consent form, agree to participate in the study, and have signed the informed consent form.

Exclusion criteria

Exclusion criteria: 1. Individuals diagnosed with underlying metabolic conditions such as obesity, type 2 diabetes, or hypertension; 2. Those with diseases potentially causing metabolic disorders, including Cushing's syndrome, hypothyroidism, hypogonadism, polycystic ovary syndrome, hypothalamic-pituitary disorders, or insulinoma; 3. Individuals undergoing long-term hormone therapy or other medication potentially affecting metabolism; 4. Alcohol abusers (consuming over 14 units of alcohol weekly; 1 unit = 360ml beer, 45ml 40% spirits, or 150ml wine); 5. Pregnant or breastfeeding women, women planning pregnancy during the trial period, or women at high risk of pregnancy without contraceptive measures; 6. Individuals with any other medical history deemed by the investigator likely to prevent adherence to or completion of the study protocol, such as hepatic or renal insufficiency, malignant tumours, cardiovascular or cerebrovascular disease, psychiatric disorders, or other serious illnesses; 7. Patients or their close relatives unable to comprehend or sign the informed consent form; 8. Individuals allergic to vitamin A; 9. Individuals taking medications that affect metabolism.

Design outcomes

Secondary

MeasureTime frame
waist circumference;hip circumference;glycemic markers;lipid metabolism markers;

Primary

MeasureTime frame
Body Mass Index (BMI);

Countries

China

Contacts

Public ContactGenqing Xie

The First People's Hospital of Xiangtan City

genqingxie@qq.com+86 181 6360 2595

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026