Femoral nerve block combined with stellate ganglion block can reduce tourniquet reaction in total knee arthroplasty

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2400082342

Enrollment

Unknown

Registered

2024-03-27

Start date

2024-03-27

Completion date

Unknown

Last updated

2024-04-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Orthopaedic anesthesia

Interventions

Stellate ganglion block and Modified femoral nerve block:Stellate ganglion block

Modified femoral nerve block:no

Eligibility

Sex/Gender

All

Age

40 Years to 70 Years

Inclusion criteria

Inclusion criteria: A total of 72 patients who underwent total knee arthroplasty between March and May of the 2024 were reviewed and approved by the Hospital Ethics Committee, and all included patients signed an informed consent form. 1. Age 40-702. Asa Class I-III 3. Patients with anesthesia time > 45 min 4. At least 72 hours in hospital after surgery. Patients undergoing elective total knee arthroplasty agreed to use nerve blocks and postoperative analgesia pumps.

Exclusion criteria

Exclusion criteria: 1. The inflating time of tourniquet is less than 45 min or more than 150 min. 2. Previous history of neurological and psychiatric disorders: brain injury, seizures, epilepsy, intracranial hypertension, cerebrovascular accident history; Or schizophrenia, mania, long-term use of psychotropic drugs, cognitive impairment history, etc. , can not read, understand and communicate 3. History of allergy to local anesthetics, skin infection at the site of puncture, or contraindications to concurrent block anesthesia. 4. Complicated with severe primary diseases such as lung, liver, kidney, cardiovascular and hematopoietic system. 5. ASA grade IV or higher 6. Bleeding Tendency or Coagulopathy.

Design outcomes

Primary

Measure	Time frame
Mean arterial pressure;Systolic blood pressure;Heart rate;	—

Secondary

Measure	Time frame
Operation Time;Anesthesia time;postoperative opioid consumption;The amount of liquid in and out;intraoperative esmolol consumption;intraoperative urapidil consumption;Time spent in recovery room;Postoperative Recovery Index;Highest Numerical Rating Scale score;Average Numerical Rating Scale score; PCA pressing frequency;sleep disturbance;Changes in inflammatory markers;Adverse reactions;POCD Incidence;Patient satisfaction;Physician satisfaction;Effective time and success rate;	—

Measure

Time frame

Operation Time;Anesthesia time;postoperative opioid consumption;The amount of liquid in and out;intraoperative esmolol consumption;intraoperative urapidil consumption;Time spent in recovery room;Postoperative Recovery Index;Highest Numerical Rating Scale score;Average Numerical Rating Scale score; PCA pressing frequency;sleep disturbance;Changes in inflammatory markers;Adverse reactions;POCD Incidence;Patient satisfaction;Physician satisfaction;Effective time and success rate;

—

Countries

China

Contacts

Public ContactLI QI

The Second Hospital of Jiaxing

532987216@qq.com+86 159 5736 2573

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026