hypertension
Conditions
Interventions
Electroacupuncture group:patients will receive electroacupuncture 3 sessions per week for 4 weeks
Sham electroacupuncture group :patients will receive sham electroacupuncture 3 sessions per week for 4 weeks
Healthy control group:NA
Sponsors
School of Acupuncture-Moxibustion and Tuina, Beijing University of Chinese Medicine
Eligibility
Sex/Gender
All
Age
25 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1. Office systolic blood pressure (SBP) from 140 to 159mm Hg and diastolic blood pressure (DBP) from 90 to 99mm Hg for patients with grade 1 primary hypertension; 2. No blood pressure medications; 3. Aged 25-60 years, male or female, right-handedness; 4. No language or intellectual disabilities, and answering and completing the questionnaires; 5. Patients who are willing to sign the informed consent.
Exclusion criteria
Exclusion criteria: 1. Other diseases that can affect the blood pressure, including but not limited to diseases of renal parenchyma, renal artery stenosis, obstructive sleep apnoea syndrome, and primary hyperaldosteronism; 2. Receiving medicines that affect blood pressure except antihypertensive drugs in last month, including but not limited to glucocorticoids and central nervous system inhibitors; 3. Uncontrolled diabetes (HbA1c=6.5%); 4. Drug or alcohol abuse; 5. Pregnant women, pregnant and lactating women; 6. Carry fMRI contraindications such as pacemakers, defibrillators, vascular clips, implanted electrical or magnetic devices, mechanical heart valves, cochlear implants, and claustrophobia; engaged in metal related work with metal fragments in the face or eyes; severe skull anatomical asymmetry or definite lesions were found in MRI scanning; cannot accept fMRI scans for other reasons; 7. History of receiving acupuncture treatment for hypertension within 3 months; 8. Participated in other clinical trials in the past 1 months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Systolic blood pressure ; | — |
Secondary
| Measure | Time frame |
|---|---|
| Diastolic blood pressure ;Short Form Health Survey 12;International Physical Activity Questionnaire;Pittsburgh Sleep Quality Index;State-Trait Anxiety Inventory-State; proportion of patients with well-controlled blood pressure;Blinding assessment;Brain magenetic resonance imaging;Pulse rate variability;Transdermal optical imaging; | — |
Countries
China
Contacts
Public ContactCunzhi Liu
School of Acupuncture-Moxibustion and Tuina, Beijing University of Chinese Medicine
Outcome results
None listed