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A randomized controlled study of topical application of zicao decoction for the treatment of skin rash after targeted medicine and immunotherapy for malignant tumors

A randomized controlled study of topical application of zicao decoction for the treatment of skin rash after targeted medicine and immunotherapy for malignant tumors

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400082307
Enrollment
Unknown
Registered
2024-03-26
Start date
2024-03-28
Completion date
Unknown
Last updated
2024-04-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

skin rash after targeted medicine and immunotherapy for malignant tumors

Interventions

Treatment group:zicao decoction
Control group:Hydrocortisone Butyrate Cream

Sponsors

Shanghai Municipal Hospital of Traditional Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 90 Years

Inclusion criteria

Inclusion criteria: ? Age greater than 18 years old; ? Patients with malignant tumors diagnosed by cytology or pathology who have undergone targeted therapy or immunotherapy; ? Meet the diagnostic criteria of rash after targeted and immunotherapy for malignant tumors; ? Disease grading meets mild or moderate, without acute skin infection and cellulitis; ? Karnofsky score = 60; ? Expected survival is more than 3 months.

Exclusion criteria

Exclusion criteria: ? Severe allergy; ? The presence of severe maculopapular rash, eczema, papular oozing, erythema, exfoliative dermatitis and other skin lesions on the localized skin of the affected limbs; ? Acute skin infections and cellulitis on the localized skin of the affected limbs; ? Combined with serious primary diseases such as cardiac, cerebrovascular, hepatic, renal and hematopoietic systems.

Design outcomes

Primary

MeasureTime frame
affected area;efficacy index;

Secondary

MeasureTime frame
basic information;safety assessment;

Countries

China

Contacts

Public ContactWeikang Zhu

Shanghai Municipal Hospital of Traditional Chinese Medicine

zwkzl5k1016@163.com+86 138 1818 6762

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026