Lateral superior arcuate ligament lumbar-square muscle block combined with esketamine in radical surgery for colorectal cancer

Lateral superior arcuate ligament lumbar-square muscle block combined with esketamine in laparoscopic radical surgery for colorectal malignancy in the elderly

Status

Recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2400082301

Enrollment

Unknown

Registered

2024-03-26

Start date

2024-04-01

Completion date

Unknown

Last updated

2024-04-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Laparoscopic radical colorectal cancer surgery

Interventions

Group Q:General anaesthesia and lumbar square muscle block over the lateral arcuate ligament (QLB-LSAL)

Group E:General anaesthesia and esketamine

Group QE:General anaesthesia and lumbar square muscle block over the lateral arcuate ligament (QLB-LSAL) and esketamine

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. patients who are going to undergo laparoscopic radical surgery for colorectal cancer under general anaesthesia, aged >65 years old, gender is not limited; 2. ASA grade ?-II, Mallampati grading grade ?-III; 3. receive postoperative patient controlled intravenous analgesia (PCIA) treatment; 4. No serious lesions of heart, lung, brain and other important organs, and no obvious abnormalities in liver and kidney functions; 5. Voluntarily participate in the clinical trial and sign the informed consent form.

Exclusion criteria

Exclusion criteria: 1. Allergies to the drugs required for use in this study; 2. Presence of infection at the puncture site; 3. Individuals with abnormal heart, liver, and kidney functions; Blood pressure = 180/100 mmHg; Untreated or poorly controlled hypertension; 4. Individuals with mental illness who are unable to cooperate; Preoperative inability to communicate due to cognitive or language impairment; 5. Other situations where the researcher determines that the patient is not suitable to participate in the clinical trial.

Design outcomes

Primary

Measure	Time frame
Pain Visual Analogue Scale;Quality of postoperative recovery;	—

Secondary

Measure	Time frame
Dosage of remifentanil and propofol during operation;Postoperative analgesic pump use: number of effective analgesic pump compressions, remedial analgesia;Operation time;Anesthesia time;Awakening time;PACU time;Untoward effect;Exhaust time;First time out of bed;Hospital stay;	—

Countries

China

Contacts

Public ContactXiaoqiong Xia

Chaohu Hospital of Anhui Medical University

xxq2366833@sina.com+86 139 6638 6669

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026