Functional abdominal distension with restrictive eating disorder and severe anxiety and depression
Conditions
Interventions
Experimental group:vagus nerve stimulators
Sponsors
Department of Digestive Surgery, Xijing Gastroenterology Hospital, Air Force Medical University, Chinese People's Liberation Army
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Diagnosis of functional abdominal distension according to Rome IV guidelines (2016). 2. Age 18-65 3. Have severe malnutrition with a BMI of less than 12kg/m2 4. After acid suppression, prokinetic and other gastroenterology departments full course of treatment, symptoms relief is less than that 30%, the BMI index does not increase. 5. After full treatment with two or more antidepressants, the symptom relief is less than that 30%, BMI does not increase.
Exclusion criteria
Exclusion criteria: 1. Women who are pregnant or breastfeeding 2. Patients at serious risk of suicide 3. Alcohol or substance dependence in the previous 12 months, or substance abuse other than nicotine in the previous 6 months 4. Cardiovascular disease (myocardial infarction or cardiac arrest), brain organic lesions (such as cerebral hemorrhage, massive cerebral infarction, encephalitis, epilepsy). 5. Accept other clinical studies
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| weight; | — |
Secondary
| Measure | Time frame |
|---|---|
| Functional magnetic resonance of the brain; | — |
Countries
china
Contacts
Public Contactzhaoqingchuan
Department of Digestive Surgery, Xijing Gastroenterology Hospital, Air Force Medical University, Chinese People's Liberation Army
Outcome results
None listed