Application and curative effect of pelvic exenteration combined with anal reconstruction in situ for rectal cancer

Status

Recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2400082291

Enrollment

Unknown

Registered

2024-03-26

Start date

2024-04-01

Completion date

Unknown

Last updated

2024-04-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Rectal cancer

Interventions

Study group:pelvic exenteration combined with anal reconstruction in situ

Eligibility

Sex/Gender

All

Age

18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Patients diagnosed with locally advanced rectal cancer or locally recurrent rectal cancer; 2. The multidisciplinary team confirmed that pelvic exenteration combined with anal reconstruction in situ was feasible; 3. Preoperative examination showed that the tumor invaded two or more pelvic organs, but the tumor was expected to be R0 resectable. 4. There were no unresectable distant metastases. 5. Patients were physically able to tolerate the surgery.

Exclusion criteria

Exclusion criteria: 1. Patients’ physical condition cannot tolerate the sugery. 2. There were unresectable distant metastases. 3. Pelvic tumor invades above the S1 or S2 nerve roots.

Design outcomes

Primary

Measure	Time frame
Postoperative complications;Postoperative anal function;	—

Secondary

Measure	Time frame
Progression Free Survival;	—

Countries

China

Contacts

Public ContactHuihong Jiang

Yangpu Hospital, Tongji University School of Medicine, Shanghai

jiang572579@163.com+86 150 0008 5783

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026