hypertriglyceridemic acute pancreatis
Conditions
Interventions
Study Group 1:Standardized treatment and Low molecular weight heparin: 100U/kg, subcutaneous injection, once a day
Study Group 2:Standardized treatment and Low molecular weight heparin: 100U/kg, subcutaneous injection, twice a day
Sponsors
Peking University Clinical Medical College of Civil Aviation (Civil Aviation General Hospital)
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: (1) diagnosis of hyperlipidaemia acute pancreatitis (2) detection of serum triglyceride within 48 hours of onset, calculated as the onset time of abdominal pain. (3) the patients and their family members were informed and signed the informed consent. (4) Age = 18 years, = 75 years.
Exclusion criteria
Exclusion criteria: (1) patients with severe heart, brain, lung, liver and kidney dysfunction before the onset of the disease, acute myocardial infarction, NYHA Heart Function Class III and above, cerebral infarction and cerebral hemorrhage, respiratory failure, Child-Pugh liver function class C, creatinine clearance less than 30 ml/min; (2) surgical intervention; (3) anticoagulant therapy before onset; (4) contraindication of anticoagulation; (5) pregnancy; (6) malignant tumor;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Organ failure; | — |
Secondary
| Measure | Time frame |
|---|---|
| Time from initiation of therapy to TG level <500 mg / dL;Local and systemic complications;Acute Physiology and Chronic Health Evaluation II Score;modified CT severity index;Ranson score;Bedside Index for Severity in Acute Pancreatitis score; | — |
Countries
China
Contacts
Public ContactCheng Jianping
Peking University Clinical Medical College of Civil Aviation (Civil Aviation General Hospital)
Outcome results
None listed