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Clinical study of different doses of esketamine combined with ropivacaine in ultrasound-guided brachial plexus nerve blocks

Clinical study of different doses of esketamine combined with ropivacaine in ultrasound-guided brachial plexus nerve blocks

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400082272
Enrollment
Unknown
Registered
2024-03-26
Start date
2024-04-01
Completion date
Unknown
Last updated
2024-04-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

upper extremity trauma

Interventions

A:Escitalopram0.2mg/kg
B:Estradiol ketamine0.3mg/kg
C:Estradiol ketamine0.4mg/kg
D: 0.375% ropivacaine 30 ml

Sponsors

Ganzhou People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: The age of the patients was 18-65 years old, and the ASA classification was I-II. The patients had no preoperative infection or tumor at the puncture site, normal coagulation function, no abnormalities in liver or kidney function, and had no history of allergy or contraindications to the anesthetic drugs in this study.

Exclusion criteria

Exclusion criteria: Patients refused brachial plexus block anesthesia; contraindications to local anesthesia or nerve puncture; potential risk of increased intracranial pressure; uncontrolled or poorly controlled hypertension; patients with hyperthyroidism; phrenic nerve anomalies or diaphragmatic dysfunction; prolonged use of analgesic medications (>2 months); and psychiatric, speech, and hearing impairments.

Design outcomes

Primary

MeasureTime frame
Time of onset and duration of motor nerve blockade;Time of onset and duration of sensory nerve blockade;

Countries

China

Contacts

Public Contactxiayanchun

Ganzhou People's Hospital

1980034728@qq.com+86 188 0797 7220

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026