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Effects of transcranial alternating current stimulation on patients with post-stroke anxiety

Effects of transcranial alternating current stimulation on patients with post-stroke anxiety

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400082252
Enrollment
Unknown
Registered
2024-03-25
Start date
2022-08-11
Completion date
Unknown
Last updated
2024-04-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

stroke

Interventions

tACS group:tACS
sham-tACS group:sham-tDAS

Sponsors

People's Liberation Army General Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 80 Years

Inclusion criteria

Inclusion criteria: According to the diagnostic criteria of stroke (including cerebral hemorrhage, cerebral infarction, cerebral embolism, etc.) made by the 4th National Cerebrovascular Conference in 1995; the onset time was more than 2 weeks and less than 2 years; A diagnosis of Depression or Anxiety is based on the Diagnostic and Statistical Manual of Mental Disorders,4th Edition, text revision (DSM-IV), and confirmed with the mini international neuropsychiatric interview 5.0 in Chinese version by at least two attending physicians or upper level; with stable vital signs, clear consciousness and no speech disorder, no audio-visual impairment; no cognitive impairment (MMSE score > 23) ; Stroke Limb Function Stage (Brunnstrom stage) > Stage I; no change in anti-anxiety or depression medication within 3 months; patients could understand and actively participate in the evaluation program; patients and family members agree and sign informed consent form.

Exclusion criteria

Exclusion criteria: The patients had emotional disorder before stroke;Mini-Mental State Examination (MMSE) < 23 points;Brunnstrom stage=Stage I; the hospital anxiety and depression scale was assessed in patients with severe mood disorders; patients with Severe Aphasia or auditory and visual impairments; patients with severe medical conditions who were currently on respiratory and cardiovascular medications;with serious internal medicine disease;patients who have undergone brain surgery, contraindications to magnetic resonance imagin or transcranial electrical stimulation (artificial pacemaker, after DBS) ;with sensitive skin, poor patient compliance; unable to complete the research as required.

Design outcomes

Primary

MeasureTime frame
Hospital Anxiety and Depression Scale (HADS);Hamilton Anxiety Scale (HAMA);Hamilton Depression Scale (HAMD);Beck Depression Inventory (BDI);Beck Anxiety Inventory (BAI);Pittsburgh sleep quality index (PSQI);safety;Sleep Quality Scale (SQS);

Secondary

MeasureTime frame
National Institute of Health stroke scale (NIHSS);Brunnstrom scale;Mini-Mental State Examination (MMSE);Barthel Index;Functional Indenpendence Measure (FIM);

Countries

China

Contacts

Public ContactLipin Huang

28, Fuxing Road, Beijing

kfyx301@126.com+86 133 9190 8450

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026