Postoperative negative behavior
Conditions
Interventions
Dexmedetomidine group:Patients were premedicated with intranasal dexmedetomidine 2 µg/kg and oral syrup 0.25 mL/kg.
Midazolam group:Patients were premedicated with intranasal 0.9% saline 0.02 mL/kg and oral midazolam 0.5 mg/kg.
Control group:Patients were premedicated with intranasal 0.9% saline 0.02 mL/kg and oral syrup 0.25 mL/kg.
Sponsors
Fujian Provincial Hospital
Eligibility
Sex/Gender
All
Age
2 Years to 5 Years
Inclusion criteria
Inclusion criteria: 1. ASA physical status I or II; 2. Aged 2-5 years; 3. Scheduled for elective tonsillectomy and (or) adenoidectomy.
Exclusion criteria
Exclusion criteria: 1. Parents refusing to allow their children to participate; 2. Intake of sedative or analgesic medication within 48 hours before surgery; 3. Developmental delay; 4. Psychosis; 5. Body mass index > 30 kg/m2; 6. Allergy to study drugs; 7. Major life changes 1 month before the operation, such as the divorce of parents, death of parents, moving to a new home, changing to a new kindergarten, etc.; 8. Any other conditions that precluded study inclusion.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of postoperative negative behavior changes; | — |
Secondary
| Measure | Time frame |
|---|---|
| Incidence of emergence delirium;Parental satisfaction;Preoperative sedation level;Incidence of postoperative negative behavior changes; | — |
Countries
China
Contacts
Public ContactYao Yusheng
Fujian Provincial Hospital
Outcome results
None listed