Study on the efficacy of transcranial alternating current stimulation in improving upper limb motor function in stroke patients

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2400082232

Enrollment

Unknown

Registered

2024-03-25

Start date

2024-04-01

Completion date

Unknown

Last updated

2024-04-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Stroke

Interventions

Experimental group:Transcranial alternating current stimulation

Control group:Sham stimulation

Eligibility

Sex/Gender

All

Age

30 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1. Ischemic/hemorrhagic stroke diagnosed by CT/MRI; 2. Age range =30 to =70 years old, with no gender limit; 3. Education level of elementary school or above; 4. First onset, with duration of disease being within 1 year, and unilateral hemiplegia; 5. Absence of obvious cognitive impairment, assessed by Mini-Mental State Examination (MMSE): primary school education level > 20 points; middle school education level > 24 points; 6. Unilateral upper limb motor dysfunction, as assessed by the short form Fugl-Meyer motor function scale (Fugl-Meyer assessment scale, FMA), upper limb part scores ranging from 0 to 66 points.

Exclusion criteria

Exclusion criteria: 1. Individuals exhibiting unstable vital signs during the acute phase 2. Individuals with aphasia, hearing impairment, or other conditions that render them unable to communicate normally with others; 3. Individuals suffering from severe bone, joint, or muscle diseases; 4. Patients diagnosed with severe organ diseases or severe mental illness; 5. Contraindications to magnetic resonance imaging include pacemakers, cardiac stents, claustrophobia, and other factors; 6. Have previously participated or are currently participating in other clinical projects within one month before enrollment.; 7. Contraindications to transcranial alternating current stimulation include cochlear implantation, a history of epilepsy, and metal implants in the body.

Design outcomes

Primary

Measure	Time frame
Fugl-Meyer assessment scale;	—

Secondary

Measure	Time frame
Action research arm test;Grip;Barthel index;Motor evoked potential;Magnetic resonance imaging;	—

Countries

China

Contacts

Public ContactXue Xin

Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine

xuexin@shutcm.edu.cn+86 152 0215 1580

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026