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A randomized controlled study of the clinical efficacy of Nd-YAP laser enhancement of apical barrier surgery in chronic apical periodontitis

A randomized controlled study of the clinical efficacy of Nd-YAP laser enhancement of apical barrier surgery in chronic apical periodontitis

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400082214
Enrollment
Unknown
Registered
2024-03-23
Start date
2024-03-25
Completion date
Unknown
Last updated
2024-03-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic periapical inflammation

Interventions

Control group:Perform root canal preparation according to conventional root canal treatment, seal the radiation-blocking calcium hydroxide paste, take CBCT to observe the shape near the apical hole be
The bleeding and hemostasis time of apical foramae were observed under microscope and dipped with paper tip. iRoot BP was filled as the apical barrier material, followed by root canal backfill and cro
Laser group:According to the conventional root canal treatment, the root canal was prepared, the radiation-blocking calcium hydroxide paste was sealed, and the morphology near the apical foramen befor

Sponsors

Peking University School and Hospital of Stomatology
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 50 Years

Inclusion criteria

Inclusion criteria: 1. A single anterior canal tooth or premolar with apical pore diameter greater than 1mm with chronic periapical inflammation caused by incomplete development or apical absorption; 2. Lesion diameter 3mm-10mm; 3. People aged 18-50 years with healthy periodontal health; 4. No diabetes and other systemic diseases affecting the healing of apical lesions;

Exclusion criteria

Exclusion criteria: 1. The patient is under 18 years old 2. Pregnant or lactating women 3. Smokers have more than 10 cigarettes per day 4. Patients with severe periodontitis and poor oral hygiene 5. Multiple adjacent affected teeth suffer from periapical inflammation

Design outcomes

Primary

MeasureTime frame
Effect of Nd-YAP laser in promoting healing of periapical lesions after apical barrier surgery;

Secondary

MeasureTime frame
The quantity of bacteria after Nd-YAP laser disinfection in apical area;Effect of Nd-YAP laser on removal of granulation in apical area during apical barrier surgery;Hemostatic effect of Nd-YAP laser on apical area during apical barrier surgery;

Countries

China

Contacts

Public ContactGong Weiyu

Peking University School and Hospital of Stomatology

kqgongweiyu@163.com+86 186 1036 7667

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026