Renal anemia
Conditions
Interventions
Enarodustat group:NA
Sponsors
Shenzhen Second People's Hospital, the First Affiliated Hospital of Shenzhen University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Patients signed informed consent file; 2. Patients diagnosed with renal anemia; 3. Aged >= 18 years; 4. The mean of the 2 most recent central laboratory hemoglobin (hemoglobin) values during the Screening Period, obtained at least 7 days apart, must have been 60-120 g/L, noninclusive. 5.Patients received Enarodustat or Roxadustat. 6.The expected survival time is more than one year.
Exclusion criteria
Exclusion criteria: 1.Patients with malignant tumor,such as prostate cancer, breast cancer, renal cell carcinoma, etc. 2.Patients with severe liver damage (Child Pugh grade C) or active hepatitis; 3.Women who are pregnant or breastfeeding; 4.Known causes for anemia other than CKD, hemosiderosis,hemochromatosis, myelodysplastic syndrome, multiple myeloma, hereditary hematologic disease such as thalassemia, sickle cell anemia, pure red cell aplasiaknown coagulation disorder, or hypercoagulable condition. 5.Hemorrhagic disorders in all their forms abd active bleeding 6. New York Heart Association Class III or IV congestive heart failure. 7. Serious infection; 8.Any red blood cell transfusion was performed 2 weeks before the start of treatment 9.Patients who are known to be allergic to the active ingredient or excipient of enarodustat or roxadustat;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Changes in hemoglobin from baseline to 7-9 week; | — |
Secondary
| Measure | Time frame |
|---|---|
| Percentage of hemoglobin > 100 g/L;haemoglobin;hypersensitive C-reactive protein;albumin;Thyroid function;Blood pressure; | — |
Countries
China
Contacts
Public ContactWan Qijun
Shenzhen Second People's Hospital, the First Affiliated Hospital of Shenzhen University
Outcome results
None listed