Hypertension
Conditions
Interventions
blood flow restriction combined with isometric resistance training group:Blood flow restriction combined with wall squat for the lower limbs, and blood flow restriction combined with handgrip for the
isometric resistance training group:Wall squat for the lower limbs, and handgrip for the upper limbs.
control group:Keep the old lifestyle.
Sponsors
Soochow University
Eligibility
Sex/Gender
All
Age
60 Years to 95 Years
Inclusion criteria
Inclusion criteria: (1) the older adults (age=60 years); (2) Meeting the diagnostic criteria for essential hypertension; (3) Having independent mobility and able to perform resistance exercises independently; (4) Informed consent and voluntary participation in this study.
Exclusion criteria
Exclusion criteria: (1) Secondary hypertension, resting SBP =160mmHg and/or DBP =100mmHg; (2) Current use of medications other than antihypertensive drugs that affect blood pressure, such as glucocorticoids, sympathomimetics, etc.; (3) History of cardiac pacemaker implantation, severe arrhythmia, heart failure, or significant organ dysfunction; (4) Body mass index >30kg/m^2; (5) Crohn's disease; history of hip, pelvic, or femoral fracture; (6) History of bleeding disorders, glaucoma, deep vein thrombosis or pulmonary embolism, smoking; (7) Major surgery within the past 6 months; (8) Participation in organized training programs within the past 6 months; (9) Cognitive impairment that prevents cooperation with researchers; (10) Sensory impairment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| blood pressure;grip strength;lower extremity knee extensor and flexor muscle strength; | — |
Secondary
| Measure | Time frame |
|---|---|
| heart rate variability;aortic pulse wave velocity;30-s chair stand test;6-minute walking test;appendicular skeletal muscle mass index;adverse event; | — |
Countries
China
Contacts
Public ContactHongyan Meng
Soochow University
Outcome results
None listed