Ventricular septal defect
Conditions
Interventions
Experimental group:The VSD was closed by percutaneous intervention with completely degradable occluder under the guidance of pure ultrasound
Control group:The VSD was closed by percutaneous intervention with conventional Nitinol occluder under the guidance of pure ultrasound
Sponsors
The First Affiliated Hospital of Guangxi Medical University
Eligibility
Sex/Gender
All
Age
1 Years to 70 Years
Inclusion criteria
Inclusion criteria: The inclusion criteria of the experimental group were: (1) age > 1 year, weight > 10kg; (2) Congenital ventricular septal defect (perimembranous type) was diagnosed with a diameter range of 3-14mm and had hemodynamic effects; ? The distance from the defect margin to the aortic valve was =3mm. (4) Subjects who can understand the purpose of the trial and voluntarily participate in and sign informed consent, and are willing to accept relevant examinations and clinical follow-up. The inclusion criteria of the control group were: (1) age > 1 year, weight > 10kg; (2) Congenital ventricular septal defect (perimembranous type) was diagnosed with a diameter range of 3-14mm and had hemodynamic effects; ? The distance from the defect margin to the aortic valve was =3mm. ? Do not agree to the use of fully degradable sealers.
Exclusion criteria
Exclusion criteria: The experimental group and the control group were excluded according to the following criteria: patients with any of the following conditions were excluded: ? mild or more aortic regurgitation; ? Severe pulmonary hypertension with bilateral shunt or right-to-left shunt; (3) Cardiac ultrasonography suggested anatomic unsuitable occlusion; Associated with ventricular septal defects or other heart malformations requiring surgical treatment; ? Infective endocarditis, or the presence of other infectious diseases.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| successful occluder implantation rate;no or less than 2mm residual shunt; | — |
Secondary
| Measure | Time frame |
|---|---|
| the rate of occluder-related complications; | — |
Countries
China
Contacts
Public ContactMai Chen
The First Affiliated Hospital of Guangxi Medical University
Outcome results
None listed