Anesthesia
Conditions
Interventions
Esketamine group:Anesthesia was induced by esketamine 0.4mg/kg IV, followed by remimazolam, cis-atracurium, and sufentanil.
Normal saline group:Anesthesia was induced by intravenous injection of the same volume of NS, followed by remimazolam, cis-atracurium, and sufentanil.
Sponsors
The First Affiliated Hospital of Guangxi Medical University Ethical Committee
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18-60; 2. ASA1-III; 3. Patients undergoing elective surgery under general anesthesia.
Exclusion criteria
Exclusion criteria: 1. Obesity; 2.Difficult airway; 3.Take analgesics; 4.Severe hypertension; 5. Lung heart illness; 6. Pulmonary hypertension; 7. Cardiac insufficiency; 8. Hyperthyroidism; 9. Epilepsy and psychosis; 10. Allergic to the drug being studied.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of hypotension after anesthesia induction; | — |
Secondary
| Measure | Time frame |
|---|---|
| Vital signs such as blood pressure, heart rate, SpO2, and BIS ;Total doses of vasoactive drugs;Total dose of anesthetic drugs;Time of loss of consciousness;Time of Bis = 60; | — |
Countries
China
Contacts
Public ContactXuehai Guan
The First Affiliated Hospital of Guangxi Medical University
Outcome results
None listed