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Real-world exploration of a 3+7 regimen in combination with Venegra in fit AML treatment

Real-world exploration of a 3+7 regimen in combination with Venegra in fit AML treatment

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2400082179
Enrollment
Unknown
Registered
2024-03-22
Start date
2024-04-15
Completion date
Unknown
Last updated
2024-03-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute myeloid leukemia (non-M3)

Interventions

Case series:NA

Sponsors

Sichuan Provincial People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 74 Years

Inclusion criteria

Inclusion criteria: (1) Patients with primary AML diagnosed according to the WHO classification criteria for tumors of hematopoietic and lymphoid tissues and treated with at least 1 course of treatment with Vinaclat in combination with the 3+7 regimen. (2) Age 18-74 years old and gender; (3) Eastern Cooperative Oncology Group (ECOG) score 0-3; (4) Patients understood and voluntarily participated in this study by signing an informed consent form.

Exclusion criteria

Exclusion criteria: (1) women who were pregnant, preparing for pregnancy, or breastfeeding; (2) with other tumors; (3) with severe organ insufficiency and an expected survival of less than 1 year; and (4) patients in whom other induction chemotherapy regimens were used during the course of treatment.

Design outcomes

Primary

MeasureTime frame
Overall response rate, ORR;

Secondary

MeasureTime frame
Progression-free survival, PFS;Overall survival, OS;

Countries

China

Contacts

Public ContactLi Hui

Department of Hematology, Sichuan Provincial People's Hospital

lihui606606@163.com+86 189 8183 8256

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026