vasoplegic syndrome
Conditions
Interventions
Posterior pituitary hormone group:Posterior pituitary hormones
Sponsors
Fuwai Hospital, Chinese Academy of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: (1) Age =18 years old, gender is not limited; (2) high-risk and severe (LVEF <50%) cardiac CPB within 24h, after adequate rehydration, there are still ? mean arterial pressure (MAP) <70mmHg; ? cardiac output index (CI) =2.5L/min/m²; ? SVRI =1200 dyn-sec/cm5/m²; ? central venous pressure (CVP) <5mmHg; ? pulmonary capillary wedge pressure ( PCWP<10mmHg; the above conditions must be satisfied at the same time; (3) Agree to sign the study informed consent form.
Exclusion criteria
Exclusion criteria: 1) Age< 18 years old; 2) preoperative co-infection; 3) presence of acute coronary syndrome before surgery; 4) malignant arrhythmia (ventricular tachycardia, ventricular fibrillation) occurred before surgery; 5) acute mesenteric ischemia before surgery; 6) preoperative renal replacement therapy; 7) Presence of endocrine or peripheral vascular disease (Raynaud's disease, etc.) before surgery; 8) the presence of other ventricular assist devices other than IABP; 9) have a history of pregnancy and tumors; 10) Refusal to sign the informed consent form for the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| ICU time ;Acute kidney injury ; | — |
Secondary
| Measure | Time frame |
|---|---|
| Acute myocardial infarction ;Arrhythmia;Low cardiac output syndrome;Stroke ;Digital and mesenteric ischemia;Ventilator assist time> 48 hours ;Hospital stay ;Hospital costs ; | — |
Countries
China
Contacts
Public ContactYanbo Zhang
Fuwai Hospital, Chinese Academy of Medical Sciences
Outcome results
None listed