lung cancer
Conditions
Interventions
Gold Standard:Take pathological diagnosis or clinical auxiliary test results as the "gold standard"
Index test:Qualitative detection of human SHOX2 gene and human RASSF1A gene methylation in human sputum, alveolar lavage fluid, and pleural effusion
Sponsors
Shanghai Tongji Hospital
Eligibility
Sex/Gender
All
Age
No minimum to 100 Years
Inclusion criteria
Inclusion criteria: Suspected patients with lung cancer who have clinical symptoms of lung cancer (such as long-term cough, hemoptysis, chest tightness, asthma, chest and back pain, etc.) but no clear diagnosis.
Exclusion criteria
Exclusion criteria: (1) The sample is less than 25mL (including preservation solution); (2) Samples in which no cells were found after centrifugation; (3) Samples with unclear sample collection time or subject case information; (4) The sample extraction volume does not meet the testing requirements in the instruction manual (the total amount of nucleic acid is insufficient or the sample is severely degraded). (5) Samples that do not meet the basic conditions for storage of test kit samples.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Positive coincidence rate and 95% CI;Negative coincidence rate and 95% CI;Total compliance rate and 95% CI;sensitivity;Specificity;Kappa value; | — |
Countries
China
Contacts
Public ContactZhiyan Liu
Shanghai Sixth People's Hospital
Outcome results
None listed