Infertility
Conditions
Interventions
Experimental group:Experimental medical device names: Semen, Cleavage Embryo Culture Medium, Blastocyst Culture Medium
Model specifications: 9340, 9310, 9312
Manufacturer: Dongyun Medical Technology (
Control group:Experimental medical device names: Semen, Cleavage Embryo Culture Medium, Blastocyst Culture Medium
Model specifications: 9340, 9310, 9312
Manufacturer: Dongyun Medical Technology (Shang
Sponsors
Nanjing Medical University First Affiliated Hospital (Jiangsu Provincial Hospital)
Eligibility
Sex/Gender
All
Age
20 Years to 40 Years
Inclusion criteria
Inclusion criteria: 1) Age <40 years old (with <35 years old accounting for 70% and =35 years old accounting for 30%); 2) Long protocol for ovulation induction, mild protocol for ovulation induction, or current center protocol; 3) =15 dominant follicles (diameter =14mm), =12 retrieved oocytes; 4) Infertility causes: a) Female: tubal inflammation, tubal adhesions, post-tubal ligation or chemical occlusion, and tubal developmental abnormalities; b) Male: normal semen parameters. 5) Female BMI index <25; 6) Couples using autologous reproductive cells for assisted reproduction; 7) Both couples signing an informed consent form.
Exclusion criteria
Exclusion criteria: 1) Infertility in individuals aged =40 years; 2) Pre-implantation genetic diagnosis screening before embryo transfer; 3) Decision to freeze oocytes on the day of egg retrieval; 4) Endometrial thickness <7mm (thin endometrium); 5) Presence of endometrial or uterine cavity abnormalities that affect embryo implantation; 6) History of giving birth to a fetus with genetic defects or chromosomal abnormalities or a history of adverse pregnancy outcomes in either partner; 7) History of drug abuse in either partner; 8) Known history of chemotherapy or radiation therapy; 9) Known refusal or inability to comply with clinical visits and examinations as required by the protocol for any reason.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The utilization rate of blastocysts can be maximized.; | — |
Secondary
| Measure | Time frame |
|---|---|
| High-quality blastocyst formation rate;Fertilization rate;Cleavage rate;Implantation rate;Clinical pregnancy rate; | — |
Countries
China
Contacts
Public ContactHu Yanqiu
Nanjing Medical University First Affiliated Hospital (Jiangsu Provincial People's Hospital)
Outcome results
None listed