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A single-center, observational study of polatuzumab vedotin-based regimen for older patients with relapsed/refractory diffuse large B-cell lymphoma

A single-center, observational study of polatuzumab vedotin-based regimen for older patients with relapsed/refractory diffuse large B-cell lymphoma

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2400082122
Enrollment
Unknown
Registered
2024-03-21
Start date
2024-03-28
Completion date
Unknown
Last updated
2024-03-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Diffuse large B cell lymphoma

Interventions

Sponsors

Beijing Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
60 Years to 120 Years

Inclusion criteria

Inclusion criteria: 1) CD20-positive diffuse large B-cell lymphoma confirmed by reference to the 5th edition of the World Health Organization (WHO) classification of neoplasms of the hematopoietic and lymphoid tissues; 2) Prior treatment with rituximab-containing therapy; 3) Age = 60 years; 4) Presence of at least one measurable lesion; 5) The patient has received or is expected to receive a polatuzumab vedotin-based regimen; 6) The patient voluntarily agrees to participate in the study and signs an informed consent form.

Exclusion criteria

Exclusion criteria: Patients or family member refuses to participate in this study.

Design outcomes

Primary

MeasureTime frame
Overall response rate;

Secondary

MeasureTime frame
2-year overall survival rate;2-year progression-free survival rate;Adverse events;

Countries

China

Contacts

Public ContactBai Jie-fei

Beijing Hospital

baijf1985@126.com+86 188 1082 2911

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026