Mild cognitive impairment
Conditions
Interventions
Normal patients:The initial concentration of sevoflurane at the end of breath is set to 2%. When the concentration reaches the set value and stabilizes for at least 15 minutes, skin cutting begins. If
If there is a positive body movement reaction, the end expiratory concentration of sevoflurane in the next patient will be increased by 0.2%
The midpoint from the patients negative reaction to the positive reaction is marked as the equilibrium point, and the experiment in this group ends at 7 equilibrium points.
mild cognitive impairment patients:The initial concentration of sevoflurane at the end of breath is set to 2%. When the concentration reaches the set value and stabilizes for at least 15 minutes, skin
mild cognitive impairment patients with sleep disorders :The initial concentration of sevoflurane at the end of breath is set to 2%. When the concentration reaches the set value and stabilizes for a
If there is a positive body movement reaction, the end expiratory conc
Sponsors
Cangzhou Central Hospital
Eligibility
Sex/Gender
Female
Age
60 Years to 75 Years
Inclusion criteria
Inclusion criteria: Patients aged 60-75 years with body mass index (BMI) of 18.5-23.9 kg/m ~ 2, ASAI/II, without visual and hearing impairment were selected for breast cancer surgery under general anesthesia in our hospital.
Exclusion criteria
Exclusion criteria: Long-term use of analgesics; mental or neurological abnormalities, recent use of anesthesia and psychotropic drugs; liver and kidney dysfunction; alcohol and drug dependence; anemia, electrolyte disorders.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Kinesthetic reaction; | — |
Secondary
| Measure | Time frame |
|---|---|
| Heart rate;Mean Arterial Pressure;Intraoperative awareness rate;Plasma orexin-A; | — |
Countries
China
Contacts
Public ContactWang Lei
Cangzhou Central Hospital
Outcome results
None listed