Neonatal respiratory failure
Conditions
Interventions
Nasal Continuous Positive Airway Pressure Group:Nasal Continuous Positive Airway Pressure
Nasal Intermittent Positive Pressure Ventilation Group:Nasal Intermittent Positive Pressure Ventilation
Sponsors
Changdu People's Hospital of Tibet
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Gestational age 24 weeks to 42 weeks, after birth to 28 days 2. Non-invasive NIPPV and NCPAP ventilation after birth 3. Postnatal patients received any mode of invasive mechanical ventilation through tracheal intubation, and the first extubation was performed to disengage from invasive ventilation 4. Parents sign informed consent.
Exclusion criteria
Exclusion criteria: 1. Congenital malformations that affect the work of breathing 2. Neuromuscular disorders that affect the work of breathing 3.The structure of upper respiratory tract was abnormal 4. Intubation is needed after extubation due to surgical procedures 5. Presence of active intraventricular hemorrhage
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Intubation rate needed within 48 hours of NIPPV and CPAP;Rate of reintubation within 48 hours after extubation;Rate of BPD;mortality;Incidence of patent ductus arteriosus; | — |
Secondary
| Measure | Time frame |
|---|---|
| Air leakage rate;Necrotizing enterocplitis; | — |
Countries
China
Contacts
Public ContactWang Yong Ming
Changdu People's Hospital of Tibet
Outcome results
None listed